S4 25 Andarine Deus Medical

S4 25 Andarine SARM Deus Medical: A Complete Guide

Type and Article: Andarine (S-4)

Andarine (S-4) is one of the earliest developed Selective Androgen Receptor Modulators (SARMs).¹

• Original Development: It was developed by GTX, Inc.² for treating conditions like muscle wasting (cachexia), osteoporosis, and benign prostatic hyperplasia (BPH).³

• Mechanism: S-4 acts as a partial agonist of the androgen receptor (AR). In certain tissues (like muscle and bone), it activates the receptor, promoting anabolic effects.⁴ In other androgenic tissues (like the prostate), it acts as a partial agonist/competitive antagonist, which theoretically limits the unwanted androgenic side effects seen with traditional anabolic steroids.⁵

• Discontinued Status: Clinical trials for Andarine were discontinued, reportedly due to findings of visual disturbances in human studies.

Why Bodybuilders Use Andarine (S-4)

Bodybuilders and athletes use Andarine primarily for its reputation as an effective agent for:

• Muscle Mass Maintenance: It is often used during “cutting” cycles where the goal is to lose body fat while strictly preserving existing lean muscle mass.

• Increased Muscle Hardness/Definition: Users report a “hardening” effect on the muscles, giving a more defined and vascular appearance.

• Moderate Anabolic Effects: Compared to other SARMs like LGD-4033 or RAD-140, its anabolic effects are considered more mild, but its partial agonist nature is thought to confer greater tissue selectivity.

Note: Andarine (S-4) is on the World Anti-Doping Agency (WADA) Prohibited List and is banned in competitive sports.

What Are the Side Effects?

The full safety profile and long-term effects of Andarine are unknown, as it never completed clinical trials. The FDA warns that SARMs carry serious risks.⁶

Distinctive and Serious Side Effects of Andarine:

• Visual Disturbances (Most Notorious): This is the key reason its clinical development was halted. Users often report altered color perception (a yellowish tint or xanthopsia) and impaired night vision (difficulty adjusting to low light).⁷ These effects are usually dose-dependent and reversible upon cessation, but they represent a clear toxicity signal.

• Testosterone Suppression: While considered less suppressive than S-23, Andarine will suppress the body’s natural testosterone production, often requiring the implementation of a Post-Cycle Therapy (PCT).

Other Potential SARMs Side Effects (Warned by FDA):

• Liver Injury: Cases of liver damage and acute liver failure have been reported with SARM use.⁸

• Cardiovascular Risk: Increased risk of heart attack or stroke.⁹

• Cholesterol Changes: Adverse impact on lipid profiles (decreased HDL, increased LDL).

• Sleep Disturbances, Sexual Dysfunction, and Infertility.¹⁰

Frequently Asked Questions (FAQs)

1. Is Andarine (S-4) a more potent SARM than Ostarine (MK-2866)?

   Andarine (S-4) is often anecdotally considered more potent for immediate strength and visual muscle “hardness” than Ostarine (MK-2866), particularly in cutting cycles. However, Ostarine is generally considered the “milder” SARM, with fewer reported severe side effects and a better track record in clinical trials, making it often preferred for a first-time SARM user.

2. Is there a safe or established dosage for Andarine?

   No. Because Andarine is an investigational, unapproved drug, there is no medically established, prescribed, or safe dosage for human consumption.11 The dosages discussed on online forums (often $25 text$ to $75 text$) are purely anecdotal and carry a high risk of adverse effects, particularly the visual disturbances.

3. What causes the visual side effects associated with S-4?

   The visual disturbances (yellow tint and night blindness) are believed to be caused by an S-4 metabolite interacting with receptors in the retina of the eye, leading to temporary visual changes.

4. Can Andarine cause liver damage?

   Yes. Like most SARMs, the FDA and various health authorities warn that the use of Andarine and other SARMs is associated with a risk of liver injury and acute liver failure.12 This underscores the significant and known danger of using these unapproved compounds.

Crucial Warning: The use of Andarine (S-4) for human consumption is highly risky. It is an unapproved, banned substance with known adverse side effects, including visual impairment and potential liver and heart issues. Consult a healthcare professional for advice on safe and legal ways to achieve your health and fitness goals.